Randomized controlled trials in cancer: Improving the quality of their reports will also facilitate better conduct
نویسندگان
چکیده
منابع مشابه
Management and Conduct of Randomized Controlled Trials Knatterud Management and Conduct of Randomized Controlled Trials
“A properly planned and executed clinical trial is a powerful experimental technique for assessing the effectiveness of an intervention” (1, p. 2). This paper will discuss the issues related to the proper planning and execution of a multicenter clinical trial. The importance of a detailed protocol and manual of operations should not be underestimated. The fundamental principles are relatively s...
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To comprehend the results of a randomized, controlled trial (RCT), readers must understand its design, conduct, analysis, and interpretation. That goal can be achieved only through complete transparency from authors. Despite several decades of educational efforts, the reporting of RCTs needs improvement. Investigators and editors developed the original CONSORT (Consolidated Standards of Reporti...
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Evaluating the effectiveness of a therapeutic intervention is ideally carried out in the setting of a randomized controlled trial (RCT). Patients are randomly allocated to the experimental and control groups ensuring that observed, pre-treatment key prognostic characteristics, but also unobserved patient characteristics, are balanced between the treatment groups, minimizing the variability in p...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1998
ISSN: 0923-7534
DOI: 10.1023/a:1008294904298